Lethal dose (LD50) is the amount of an ingested substance that kills 50 percent of a test sample. It is expressed in mg/kg, or milligrams of substance per kilogram of body weight.

***Due to law many drugs are unable to be determined what the LD50 is.

 Aspirin

LD50 200 mg/kg (rat, oral)

Gastric distress, confusion, psychosis, stupor, ringing in ears, drowsiness, hyperventilation

Sodium chloride (Salt)

12357 mg/kg (human, oral)

Eye irritant, elevated blood pressure

Glucose (sugar)

LD50 30 g/kg (rat, oral)

Depressed activity, gastrointestinal disturbances. If diabetic- heart disease, blindness, nerve damage, kidney damage

Ethanol (alchohol) 

LD50 7060 mg/kg (rat, oral)

Nausea, headache, vomiting, dizziness, nervous system depression, confusion, loss of consciousness

Caffeine

LD50 140 mg/kg (dog, oral)

Acute renal failure, nausea, psychosis, hemorrhage, increased pulse, convulsions